Downregulation of IRAK3 by miR-33b-3p relieves chondrocyte inflammation and apoptosis in an in vitro osteoarthritis model

Interleukin-1 receptor-associated kinase-3 (IRAK3) has a particular position in regulating irritation. Nevertheless, the practical position of IRAK3 and regulatory mechanism underlying the pathogenesis of osteoarthritis (OA) stay unclear. Right here, we first discovered that IRAK3 was upregulated, whereas miR-33b-3p was downregulated within the cartilage of OA sufferers and IL-1β-induced CHON-001 cells.

IRAK3 was confirmed because the direct goal of miR-33b-3p and negatively regulated by miR-33b-3p. There was an inverse correlation between IRAK3 mRNA expression and miR-33b-3p expression in OA cartilage tissues. The in vitro practical experiments confirmed that miR-33b-3p overexpression precipitated a exceptional enhance in viability, a big lower in inflammatory mediators (IL-1β and TNF-α), and apoptosis in IL-1β-induced CHON-001 cells. Importantly, IRAK3 knockdown imitated, whereas overexpression reversed the results of miR-33b-3p on IL-1β-induced irritation and apoptosis in CHON-001 cells. Collectively, miR-33b-3p considerably alleviated IL-1β-induced irritation and apoptosis by downregulating IRAK3, which can function a promising goal for OA.

USP7 Inhibition Alleviates H 2 O 2-Induced Damage in Chondrocytes through Inhibiting NOX4/NLRP3 Pathway

Osteoarthritis (OA), the most typical type of arthritis, is a quite common joint illness that usually impacts middle-aged to aged folks. Nevertheless, present remedy choices for OA are predominantly palliative. Thus, understanding its pathological course of and exploring its potential therapeutic approaches are of nice significance. Rat chondrocytes have been remoted and uncovered to hydrogen peroxide (H2O2) to imitate OA. The consequences of H2O2 on ubiquitin-specific protease 7 (USP7) expression, reactive oxygen species (ROS) ranges, proliferation, inflammatory cytokine launch, and pyroptosis have been measured.

USP7 was knocked down (KD) or overexpressed to research the position of USP7 in OA. Co-immunoprecipitation (Co-IP) was used to check the interplay between USP7 and NAD(P)H oxidases (NOX)four in addition to NOX4 ubiquitination. NOX4 inhibitor was utilized to check the involvement of NOX4 in USP7-mediated OA improvement. USP7 inhibitor was given to OA animals to additional examine the position of USP7 in OA in vivo.

Furthermore, H2O2 remedy considerably elevated USP7 expression, enhanced ROS ranges, and inhibited proliferation in rat chondrocytes. The overexpression of USP7 enhanced pyroptosis, ROS manufacturing, interleukin (IL)-1β and IL-18 ranges, and the expression degree of NLRP3, GSDMD-N, energetic caspase-1, pro-caspase-1, matrix metalloproteinases (MMP) 1, and MMP13, which was abolished by ROS inhibition. The USP7 KD protected rat chondrocytes in opposition to H2O2-induced harm. Co-IP outcomes confirmed that USP7 interacted with NOX4, and USP7 KD enhanced NOX4 ubiquitinylation.

The inhibition of NOX4 blocked the pro-OA impact of USP7. Furthermore, the USP7 inhibitor given to OA animals suppressed OA in vivo. USP7 inhibited NOX4 ubiquitination for degradation which results in elevated ROS manufacturing. ROS subsequently prompts NLPR3 inflammasome, resulting in enhanced manufacturing of IL-1β and IL-18, GSDMD-N-dependent pyroptosis, and extracellular matrix reworking. Thus, UPS7 contributes to the development of OA through NOX4/ROS/NLPR3 axis.

Acid-Sensing Ion Channel-1a in Articular Chondrocytes and Synovial Fibroblasts: A Novel Therapeutic Goal for Rheumatoid Arthritis

Acid-sensing ion channel 1a (ASIC1a) is a member of the extracellular H+-activated cation channel household. Rising proof has urged that ASIC1a performs a vital position within the pathogenesis of rheumatoid arthritis (RA). Particularly, ASIC1a might promote irritation, synovial hyperplasia, articular cartilage, and bone destruction; these result in the development of RA, a continual autoimmune illness characterised by continual synovial irritation and extra-articular lesions.

On this evaluation, we offered a quick overview of the molecular properties of ASIC1a, together with the essential organic traits, tissue and cell distribution, channel blocker, and elements influencing the expression and performance, and centered on the potential therapeutic targets of ASIC1a in RA and doable mechanisms of blocking ASIC1a to enhance RA signs, akin to regulation of apoptosis, autophagy, pyroptosis, and necroptosis of articular cartilage, and synovial irritation and invasion of fibroblast-like cells in synovial tissue.

Downregulation of IRAK3 by miR-33b-3p relieves chondrocyte inflammation and apoptosis in an in vitro osteoarthritis model

Protecting Impact of Pyrroloquinoline Quinone on TNF-α-induced Mitochondrial Damage in Chondrocytes

Osteoarthritis (OA) is a degenerative illness characterised by matrix degradation and cell loss of life resulting in a gradual lack of articular cartilage integrity. As a bacterial synthesis of quinine, pyrroloquinoline quinone (PQQ) is a robust redox cofactor with a wide range of organic advantages, together with antioxidant, anti-inflammation-induced mitochondrial metabolism regulation.

This examine was designed to research the impact of PQQ on TNF-α-induced mitochondrial injury in chondrocytes. Chondrocytes remoted from C57BL/6 mice have been uncovered to TNF-α 50 ng/mL, TNF-α 50 ng/mL + PQQ 10 µmol/L for 24 h. Then, morphological examine, practical examine and mechanism examine have been taken. The outcomes revealed TNF-α-induced chondrocyte mitochondrion injury could possibly be lowered by utility of PQQ, evidenced by elevated variety of mitochondria, well-kept mtDNA integrity, preserved ATP degree, reestablished mitochondrial membrane potential, and prevented mitochondrial perform.

anti-Activator of basal transcription 1
YF-PA18596 50 ul
EUR 435.6
Description: Mouse polyclonal to Activator of basal transcription 1

anti-Activator of basal transcription 1
YF-PA18597 50 ug
EUR 435.6
Description: Mouse polyclonal to Activator of basal transcription 1

anti-Activator of basal transcription 1
YF-PA18598 50 ul
EUR 435.6
Description: Mouse polyclonal to Activator of basal transcription 1

anti-Activator of basal transcription 1
YF-PA18599 50 ug
EUR 435.6
Description: Mouse polyclonal to Activator of basal transcription 1

Activator of Basal Transcription 1 (ABT1) Antibody
20-abx110789
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Activator of Basal Transcription 1 (ABT1) Antibody
20-abx004524
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Activator of Basal Transcription 1 (ABT1) Antibody
abx037021-100ug 100 ug
EUR 469.2

Activator of Basal Transcription 1 (ABT1) Antibody
abx230056-100ug 100 ug
EUR 577.2

Activator Of Basal Transcription 1 (ABT1) Antibody
20-abx338734
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Activator Of Basal Transcription 1 (ABT1) Antibody (HRP)
20-abx334566
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Activator Of Basal Transcription 1 (ABT1) Antibody (FITC)
20-abx334567
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Activator Of Basal Transcription 1 (ABT1) Antibody (Biotin)
20-abx334568
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Activator of basal transcription 1(ABT1) ELISA kit
E01A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Activator of basal transcription 1(ABT1) ELISA kit
E01A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Activator of basal transcription 1(ABT1) ELISA kit
E01A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Activator of basal transcription 1(ABT1) ELISA kit
E02A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Activator of basal transcription 1(ABT1) ELISA kit
E02A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Activator of basal transcription 1(ABT1) ELISA kit
E02A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Activator of basal transcription 1(ABT1) ELISA kit
E07A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Activator of basal transcription 1(ABT1) ELISA kit
E07A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Activator of basal transcription 1(ABT1) ELISA kit
E07A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Activator of basal transcription 1(ABT1) ELISA kit
E04A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Activator of basal transcription 1(ABT1) ELISA kit
E04A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Activator of basal transcription 1(ABT1) ELISA kit
E04A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Activator of basal transcription 1(ABT1) ELISA kit
E08A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Activator of basal transcription 1(ABT1) ELISA kit
E08A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Activator of basal transcription 1(ABT1) ELISA kit
E08A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Activator of basal transcription 1(ABT1) ELISA kit
E06A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Activator of basal transcription 1(ABT1) ELISA kit
E06A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Activator of basal transcription 1(ABT1) ELISA kit
E06A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Activator of basal transcription 1(ABT1) ELISA kit
E09A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Activator of basal transcription 1(ABT1) ELISA kit
E09A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Activator of basal transcription 1(ABT1) ELISA kit
E09A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Activator of basal transcription 1(ABT1) ELISA kit
E03A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Activator of basal transcription 1(ABT1) ELISA kit
E03A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Activator of basal transcription 1(ABT1) ELISA kit
E03A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Activator Of Basal Transcription 1 (ABT1) ELISA Kit
abx385562-96tests 96 tests
EUR 1093.2

Bovine Activator of basal transcription 1, ABT1 ELISA KIT
ELI-24538b 96 Tests
EUR 1113.6

Mouse Activator of basal transcription 1, Abt1 ELISA KIT
ELI-24666m 96 Tests
EUR 1038

Human Activator of basal transcription 1, ABT1 ELISA KIT
ELI-24776h 96 Tests
EUR 988.8

BME 100X Amino Acids for Basal Medium Eagle (Modified). W/O L-glutamine.
BML02-500ML 500 ml
EUR 124.8
Description: 100X Amino Acids for Basal Medium Eagle (Modified). Without L-glutamine.

Guinea pig Activator of basal transcription 1(ABT1) ELISA kit
E05A1165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Activator of basal transcription 1(ABT1) ELISA kit
E05A1165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Activator of basal transcription 1(ABT1) ELISA kit
E05A1165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anderson's Basal Salt
CP001-010 10x1L
EUR 118.8

Anderson's Basal Salt
CP001-500 50L
EUR 151.2

Anderson's Basal Salt
CP002-010 10X1L
EUR 118.8

Anderson's Basal Salt
CP002-500 50L
EUR 151.2

ENDO Basal Media
MED002 500 ml
EUR 248.4

Pericyte Basal Media
PGB002 475 ml
EUR 325.2

Astrocyte Basal Media
PGB004 500 ml
EUR 325.2

DKW Basal Salt Mixture
CP007-010 10X1L
EUR 118.8

DKW Basal Salt Mixture
CP007-500 50L
EUR 151.2

Basal Cell Cytokeratin antibody
10R-7959 100 ug
EUR 444
Description: Mouse monoclonal Basal Cell Cytokeratin antibody

Basal Body Marker antibody
10-2480 250 ug
EUR 590.4
Description: Mouse monoclonal Basal Body Marker antibody

A Medium
DJ1018 100g
EUR 101.76

DC MEDIUM
D04-117-10kg 10 kg
EUR 1894.8

DC MEDIUM
D04-117-2kg 2kg
EUR 458.4

DC MEDIUM
D04-117-500g 500 g
EUR 168

Advanced Medium
C0003-04 RT 500 mL Bottle
EUR 123.6

Medium 199
C0012-01 RT 500 mL Bottle
EUR 126

COLIFORM MEDIUM
C03-127-10kg 10 kg
EUR 1588.8

COLIFORM MEDIUM
C03-127-2kg 2kg
EUR 392.4

COLIFORM MEDIUM
C03-127-500g 500 g
EUR 150

Heller's Medium
CP014-010 10X1L
EUR 118.8

Heller's Medium
CP014-500 50L
EUR 151.2

Hoagland's Medium
CP015-010 10X1L
EUR 118.8

Hoagland's Medium
CP015-500 50L
EUR 151.2

EC MEDIUM
E05-100-10kg 10 kg
EUR 976.8

EC MEDIUM
E05-100-2Kg 2 Kg
EUR 259.2

EC MEDIUM
E05-100-500g 500 g
EUR 114

Mounting Medium
4300 3 ml
EUR 216.6
Description: This is Mounting medium (non-fading) used for maintaining optimal conditions needed to obtain the maximum fluorescence emission from Fluorescein.

NeuroProgenitor Medium
NM42400 125 ml
EUR 364.8

HLP MEDIUM
H08-107-10kg 10 kg
EUR 2733.6

HLP MEDIUM
H08-107-2Kg 2 Kg
EUR 640.8

HLP MEDIUM
H08-107-500g 500 g
EUR 218.4

SIM MEDIUM
S19-110-10kg 10 kg
EUR 1225.2

SIM MEDIUM
S19-110-2kg 2kg
EUR 313.2

SIM MEDIUM
S19-110-500g 500 g
EUR 128.4

SOB MEDIUM
S19-124-10kg 10 kg
EUR 1158

SOB MEDIUM
S19-124-2kg 2kg
EUR 298.8

SOB MEDIUM
S19-124-500g 500 g
EUR 124.8

M9 Medium
SD7024 250g
EUR 86.1

M9CA Medium
SD7025 250g
EUR 86.1

YM Medium
SD7031 250g
EUR 84.54

TYGPN Medium
SD7032 250g
EUR 84.01

M63 Medium
SD7033 250g
EUR 86.1

TCBS Medium
MED1188 PK10
EUR 7.52

DNase Medium
MED1196 PK10
EUR 7.98

Cancer of the breast, basal-like breast carcinoma, 48 cases (1.5mm), set 1
BRC965 1
EUR 492
Description: Breast cancer tissue array, basal-like breast carcinoma, 48 cases (1.5mm), set 1, 96 cores, 48 cases, containing 35 cases basal-like, 3 cases luminal A, 3 cases luminal B, 4 cases Her2 overexpression types and 1 case Adenoid cystic carcinoma for positive control, with grading, TNM staging, and ER, PR, HER2, P53, EGFR, Ki67,CK5/6 and Nestin IHC data.

Basal Cell Adhesion Molecule/CD239
PR27244 2 ug
EUR 229.2

Anti-Basal cell Cytokeratin antibody
STJ16100229 100 µg
EUR 536.4

500mL Gracess Insect Basal Medi
13-200-CV PK6
EUR 353.4

Insect Cell Medium: TNM-FH Insect Culture Medium
ABP-MED-10001 1 liter Ask for price

Insect Cell Medium: Serum-Free Insect Culture Medium
ABP-MED-10002 1 liter Ask for price

Insect Cell Medium: Grace?s Insect Medium (Unsupplemented)
ABP-MED-10004 1 liter Ask for price

MCDB 131 Medium
CM034-050 500ml
EUR 102

MCDB 131 Medium
CM034-300 6x500ml
EUR 198

MCDB 131 Medium
CM034-310 10x500ml
EUR 262.8

MCDB 131 Medium
CM034-320 20x500ml
EUR 408

MCDB 131 Medium
CM034-350 50x500ml
EUR 702

Williams' Medium E
CM063-050 500ml
EUR 109.2

Williams' Medium E
CM063-300 6x500ml
EUR 319.2

Williams' Medium E
CM063-310 10x500ml
EUR 375.6

Williams' Medium E
CM063-320 20x500ml
EUR 724.8

Williams' Medium E
CM063-350 50x500ml
EUR 1170

H Medium Broth
DJ1019 100g
EUR 73.06

AddexBio Cryopreservation Medium
C0002-20mL RT vial
EUR 124.8

CARY & BLAIR MEDIUM
C03-131-10kg 10 kg
EUR 2622

CARY & BLAIR MEDIUM
C03-131-2Kg 2 Kg
EUR 616.8

CARY & BLAIR MEDIUM
C03-131-500g 500 g
EUR 211.2

Cereal Crops Medium
CP003-005 5L
EUR 135.6

Cereal Crops Medium
CP003-010 10X1L
EUR 202.8

Kao Michayluk Medium
CP017-010 10X1L
EUR 118.8

Kao Michayluk Medium
CP017-500 50L
EUR 151.2

Orchid Maintenance Medium
CP037-010 10X1L
EUR 130.8

Orchid Maintenance Medium
CP037-500 50L
EUR 165.6

Woody Plants Medium
CP040-010 10X1L
EUR 121.2

Woody Plants Medium
CP040-500 50L
EUR 151.2

EC MEDIUM, MODIFIED
E05-108-10kg 10 kg
EUR 1029.6

EC MEDIUM, MODIFIED
E05-108-2Kg 2 Kg
EUR 271.2

EC MEDIUM, MODIFIED
E05-108-500g 500 g
EUR 117.6

FLUID THIOGLYCOLLATE MEDIUM
F06-101-10kg 10 kg
EUR 950.4

FLUID THIOGLYCOLLATE MEDIUM
F06-101-2kg 2kg
EUR 253.2

FLUID THIOGLYCOLLATE MEDIUM
F06-101-500g 500 g
EUR 112.8

FluoreGuard Mounting Medium
FMM030 30 ml
EUR 115.2

FluoreGuard Mounting Medium
FMM060 60 ml
EUR 139.2

FluoreGuard Mounting Medium
FMM500 500 ml
EUR 392.4

FluoreGuard Mounting Medium
FMM999 1000 ml
EUR 636

Recovery Medium - 6x12mL
1711 4/PK
EUR 153.6

A-1 MEDIUM
A01-116-10kg 10 kg
EUR 1240.8

A-1 MEDIUM
A01-116-2Kg 2 Kg
EUR 316.8

A-1 MEDIUM
A01-116-500g 500 g
EUR 129.6

Aqueous Mounting Medium
AR1018 10mL X5 (Enough for 800-1200 assays)
EUR 96

Antifade Mounting Medium
AR1109 10mL (for 1000 assays)
EUR 78

MOTILITY TEST MEDIUM
M13-121-10kg 10 kg
EUR 1833.6

MOTILITY TEST MEDIUM
M13-121-2Kg 2 Kg
EUR 445.2

MOTILITY TEST MEDIUM
M13-121-500g 500 g
EUR 164.4

Hepatocyte Maintenance Medium
HM42600 100 ml
EUR 490.8

Neuron Growth Medium
HNM001 500 ml
EUR 397.2

Agarose, medium EEO
GE4750-100G 100 g
EUR 199.2

Agarose, medium EEO
GE4750-500G 500 g
EUR 514.8

REINFORCED CLOSTRIDIUM MEDIUM
R18-105-10kg 10 kg
EUR 1432.8

REINFORCED CLOSTRIDIUM MEDIUM
R18-105-2kg 2kg
EUR 358.8

REINFORCED CLOSTRIDIUM MEDIUM
R18-105-500g 500 g
EUR 141.6

Schwann Growth Medium
SGM001 500 ml
EUR 292.8

Sepadextran-25 Medium
SD25M-100 100 g
EUR 325.2

Sepadextran-25 Medium
SD25M-500 500 g
EUR 1243.2

Sepadextran-50 Medium
SD50M-100 100 g
EUR 412.8

Sepadextran-50 Medium
SD50M-500 500 g
EUR 1542

TERRIFIC BROTH MEDIUM
T20-114-10kg 10 kg
EUR 810

TERRIFIC BROTH MEDIUM
T20-114-2kg 2kg
EUR 223.2

TERRIFIC BROTH MEDIUM
T20-114-500g 500 g
EUR 104.4

THIOGLYCOLLATE MEDIUM, BREWER
T20-118-10kg 10 kg
EUR 1636.8

THIOGLYCOLLATE MEDIUM, BREWER
T20-118-2kg 2kg
EUR 403.2

THIOGLYCOLLATE MEDIUM, BREWER
T20-118-500g 500 g
EUR 153.6

2XYT MICROBIAL MEDIUM
X24-102-10kg 10 kg
EUR 736.8

2XYT MICROBIAL MEDIUM
X24-102-2Kg 2 Kg
EUR 207.6

2XYT MICROBIAL MEDIUM
X24-102-500g 500 g
EUR 99.6

Lowenstein-Jensen Medium
MED1400 EACH
EUR 114

Sabouraud Liquid Medium
MED1462 EACH
EUR 54.61

Slanetz & Bartley Medium
MED1468 EACH
EUR 107.16

Dermatophyte Test Medium
MED1484 EACH
EUR 87.78

Edwardsiella ictaluri Medium
MED1634 500G
EUR 125.4

10mL S.O.C. Medium
46-003-CR PK10
EUR 110.58

Ec Medium 500gm
231430 EACH
EUR 149.34

Difco 2xYT Medium
244020 EACH
EUR 118.56

Sob Medium 500gm
244310 EACH
EUR 234.84

Legionella GVPC medium
257007 PK20
EUR 99.18

SuperMOUNT? Mounting Medium
1211-20 each
EUR 241.2

RPMI 1640 Medium
abx098879-500ml 500 ml
EUR 210

Thaw Medium 4
60181-1 100 ml
EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• CFTR - HEK 293 Recombinant Cell Line #60506• Nav1.8/β2 - HEK293 Recombinant Cell Line #60521• NaV1.7-HEK293 Recombinant Cell Line #60607

Thaw Medium 4
60181-2 500 ml
EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• CFTR - HEK 293 Recombinant Cell Line #60506• Nav1.8/β2 - HEK293 Recombinant Cell Line #60521• NaV1.7-HEK293 Recombinant Cell Line #60607

Thaw Medium 5
60182-1 100 ml
EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Gli Reporter - NIH3T3 Recombinant Cell line (Hedgehog Pathway) #60409

Thaw Medium 5
60182-2 500 ml
EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Gli Reporter - NIH3T3 Recombinant Cell line (Hedgehog Pathway) #60409

Thaw Medium 6
60183-1 100 ml
EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520• NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 • RARα Reporter - HEK293 Recombinant Cell Line #60503 • RARβ Reporter - HEK293 Recombinant Cell Line #60603 • RARγ Reporter - HEK293 Reporter Cell Line #60604

Thaw Medium 6
60183-2 500 ml
EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520• NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 • RARα Reporter - HEK293 Recombinant Cell Line #60503 • RARβ Reporter - HEK293 Recombinant Cell Line #60603 • RARγ Reporter - HEK293 Reporter Cell Line #60604

Thaw Medium 2
60184-1 100 ml
EUR 150
Description: This liquid Cell Thawing Medium is optimized for thawing and plating BPS Bioscience's Jurkat-based cell lines, including• PD-1/NFAT Reporter-Jurkat cell #60535• NFAT Reporter (Luc) - Jurkat Cell Line #60621• NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line #60651• ADCC Bioassay Effector Cell F variant (Low Affinity) #60540• ADCC Bioassay Effector Cell V variant (High Affinity) #60541Note: once cells are well-established, switch to the appropriate cell growth medium.

Thaw Medium 2
60184-2 500 ml
EUR 675
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including_x000D__x000D_• PD-1/NFAT Reporter-Jurkat cell #60535_x000D__x000D_• NFAT Reporter (Luc) - Jurkat Cell Line #60621_x000D__x000D_• NF-ĸB-Luciferase Reporter (Luc) - Jurkat Cell Line #60651_x000D__x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) #60540_x000D__x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) #60541_x000D__x000D_Note: once cells are well-established, switch to the appropriate cell growth medium.

Thaw Medium 7
60185-1 100 ml
EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520 • NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623

Thaw Medium 7
60185-2 500 ml
EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including • Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520 • NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623

Thaw Medium 3
60186-1 100 ml
EUR 150
Description: This liquid Cell Thaw Medium is optimized for thawing and plating BPS Bioscience's CHO cell-based recombinant cell lines, including• TCR Activator - CHO Recombinant Cell line #60539 • TCR activator / PD-L1 - CHO Recombinant Cell line #60536 It is designed for use in a 37°C incubator with an atmosphere of 5% CO2/95% air. Note: once cells are well established, switch to an appropriate cell growth medium.

Thaw Medium 3
60186-2 500 ml
EUR 645
Description: This liquid thaw medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including_x000D__x000D_• TCR Activator - CHO Recombinant Cell line #60539 _x000D_• TCR activator / PD-L1 - CHO Recombinant Cell line #60536 _x000D__x000D_• CD27 CHO-K1 Stable Recombiant Cell Line #60624 _x000D__x000D_• PD-L1 - CHO Recombinant Cell Line #60543 _x000D__x000D_• NF-κB Reporter (Luc) - CHO-K1 Recombinant Cell Line #60622_x000D_• CD137L (4-1BBL) CHO-K1 Recombinant Cell Line #60523_x000D__x000D_It is designed for use in a 37°C incubator with an atmosphere of 5% CO2/95% air. _x000D_Note: once cells are well established, switch to an appropriate cell growth medium._x000D_

Thaw Medium 1
60187-1 100 ml
EUR 155
Description: This liquid HEK293 Cell Thawing Medium is optimized for thawing and plating BPS Bioscience's HEK293 recombinant cell lines.

Thaw Medium 1
60187-2 500 ml
EUR 695
Description: This liquid Thaw Medium is optimized for thawing and plating BPS Bioscience's HEK293 recombinant cell lines.

Growth Medium 3A
60188 500 ml
EUR 755
Description: This liquid Growth Medium is a complete medium optimized to culture select CHO and CHO-K1 cell lines.

The current work strongly means that the mitochondrion is a vital goal for OA chondrocyte injury induced by TNF-α and the PQQ safety from this injury ameliorates mitochondrial dysfunction induced by TNF-α. PQQ may be a possible chemical for OA intervention.

 

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