Interleukin-1 receptor-associated kinase-3 (IRAK3) has a particular position in regulating irritation. Nevertheless, the practical position of IRAK3 and regulatory mechanism underlying the pathogenesis of osteoarthritis (OA) stay unclear. Right here, we first discovered that IRAK3 was upregulated, whereas miR-33b-3p was downregulated within the cartilage of OA sufferers and IL-1β-induced CHON-001 cells.
IRAK3 was confirmed because the direct goal of miR-33b-3p and negatively regulated by miR-33b-3p. There was an inverse correlation between IRAK3 mRNA expression and miR-33b-3p expression in OA cartilage tissues. The in vitro practical experiments confirmed that miR-33b-3p overexpression precipitated a exceptional enhance in viability, a big lower in inflammatory mediators (IL-1β and TNF-α), and apoptosis in IL-1β-induced CHON-001 cells. Importantly, IRAK3 knockdown imitated, whereas overexpression reversed the results of miR-33b-3p on IL-1β-induced irritation and apoptosis in CHON-001 cells. Collectively, miR-33b-3p considerably alleviated IL-1β-induced irritation and apoptosis by downregulating IRAK3, which can function a promising goal for OA.
USP7 Inhibition Alleviates H 2 O 2-Induced Damage in Chondrocytes through Inhibiting NOX4/NLRP3 Pathway
Osteoarthritis (OA), the most typical type of arthritis, is a quite common joint illness that usually impacts middle-aged to aged folks. Nevertheless, present remedy choices for OA are predominantly palliative. Thus, understanding its pathological course of and exploring its potential therapeutic approaches are of nice significance. Rat chondrocytes have been remoted and uncovered to hydrogen peroxide (H2O2) to imitate OA. The consequences of H2O2 on ubiquitin-specific protease 7 (USP7) expression, reactive oxygen species (ROS) ranges, proliferation, inflammatory cytokine launch, and pyroptosis have been measured.
USP7 was knocked down (KD) or overexpressed to research the position of USP7 in OA. Co-immunoprecipitation (Co-IP) was used to check the interplay between USP7 and NAD(P)H oxidases (NOX)four in addition to NOX4 ubiquitination. NOX4 inhibitor was utilized to check the involvement of NOX4 in USP7-mediated OA improvement. USP7 inhibitor was given to OA animals to additional examine the position of USP7 in OA in vivo.
Furthermore, H2O2 remedy considerably elevated USP7 expression, enhanced ROS ranges, and inhibited proliferation in rat chondrocytes. The overexpression of USP7 enhanced pyroptosis, ROS manufacturing, interleukin (IL)-1β and IL-18 ranges, and the expression degree of NLRP3, GSDMD-N, energetic caspase-1, pro-caspase-1, matrix metalloproteinases (MMP) 1, and MMP13, which was abolished by ROS inhibition. The USP7 KD protected rat chondrocytes in opposition to H2O2-induced harm. Co-IP outcomes confirmed that USP7 interacted with NOX4, and USP7 KD enhanced NOX4 ubiquitinylation.
The inhibition of NOX4 blocked the pro-OA impact of USP7. Furthermore, the USP7 inhibitor given to OA animals suppressed OA in vivo. USP7 inhibited NOX4 ubiquitination for degradation which results in elevated ROS manufacturing. ROS subsequently prompts NLPR3 inflammasome, resulting in enhanced manufacturing of IL-1β and IL-18, GSDMD-N-dependent pyroptosis, and extracellular matrix reworking. Thus, UPS7 contributes to the development of OA through NOX4/ROS/NLPR3 axis.
Acid-Sensing Ion Channel-1a in Articular Chondrocytes and Synovial Fibroblasts: A Novel Therapeutic Goal for Rheumatoid Arthritis
Acid-sensing ion channel 1a (ASIC1a) is a member of the extracellular H+-activated cation channel household. Rising proof has urged that ASIC1a performs a vital position within the pathogenesis of rheumatoid arthritis (RA). Particularly, ASIC1a might promote irritation, synovial hyperplasia, articular cartilage, and bone destruction; these result in the development of RA, a continual autoimmune illness characterised by continual synovial irritation and extra-articular lesions.
On this evaluation, we offered a quick overview of the molecular properties of ASIC1a, together with the essential organic traits, tissue and cell distribution, channel blocker, and elements influencing the expression and performance, and centered on the potential therapeutic targets of ASIC1a in RA and doable mechanisms of blocking ASIC1a to enhance RA signs, akin to regulation of apoptosis, autophagy, pyroptosis, and necroptosis of articular cartilage, and synovial irritation and invasion of fibroblast-like cells in synovial tissue.

Protecting Impact of Pyrroloquinoline Quinone on TNF-α-induced Mitochondrial Damage in Chondrocytes
Osteoarthritis (OA) is a degenerative illness characterised by matrix degradation and cell loss of life resulting in a gradual lack of articular cartilage integrity. As a bacterial synthesis of quinine, pyrroloquinoline quinone (PQQ) is a robust redox cofactor with a wide range of organic advantages, together with antioxidant, anti-inflammation-induced mitochondrial metabolism regulation.
This examine was designed to research the impact of PQQ on TNF-α-induced mitochondrial injury in chondrocytes. Chondrocytes remoted from C57BL/6 mice have been uncovered to TNF-α 50 ng/mL, TNF-α 50 ng/mL + PQQ 10 µmol/L for 24 h. Then, morphological examine, practical examine and mechanism examine have been taken. The outcomes revealed TNF-α-induced chondrocyte mitochondrion injury could possibly be lowered by utility of PQQ, evidenced by elevated variety of mitochondria, well-kept mtDNA integrity, preserved ATP degree, reestablished mitochondrial membrane potential, and prevented mitochondrial perform.
BME 100X Vitamins for Basal Medium Eagle (Modified) |
BML01-100ML |
Caisson Labs |
100 ml |
EUR 73 |
- Product line: Animal Cell Culture Media
- Product family: Basal Medium Eagle
|
Description: 100X Vitamins for Basal Medium Eagle (Modified) |
BME 100X Vitamins for Basal Medium Eagle (Modified) |
BML01-500ML |
Caisson Labs |
500 ml |
EUR 92 |
- Product line: Animal Cell Culture Media
- Product family: Basal Medium Eagle
|
Description: 100X Vitamins for Basal Medium Eagle (Modified) |
anti-Activator of basal transcription 1 |
YF-PA18596 |
Abfrontier |
50 ul |
EUR 363 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
anti-Activator of basal transcription 1 |
YF-PA18597 |
Abfrontier |
50 ug |
EUR 363 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
anti-Activator of basal transcription 1 |
YF-PA18598 |
Abfrontier |
50 ul |
EUR 363 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
anti-Activator of basal transcription 1 |
YF-PA18599 |
Abfrontier |
50 ug |
EUR 363 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
Activator of Basal Transcription 1 (ABT1) Antibody |
20-abx110789 |
Abbexa |
|
|
- Shipped within 5-10 working days.
|
Activator of Basal Transcription 1 (ABT1) Antibody |
abx037021-100ug |
Abbexa |
100 ug |
EUR 391 |
- Shipped within 5-10 working days.
|
Activator of Basal Transcription 1 (ABT1) Antibody |
20-abx004524 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
-
100 ul
-
200 ul
-
20 ul
-
50 ul
|
- Shipped within 5-10 working days.
|
Activator Of Basal Transcription 1 (ABT1) Antibody |
20-abx338734 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
Activator of Basal Transcription 1 (ABT1) Antibody |
abx230056-100ug |
Abbexa |
100 ug |
EUR 481 |
- Shipped within 5-12 working days.
|
Activator Of Basal Transcription 1 (ABT1) Antibody (HRP) |
20-abx334566 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
Activator Of Basal Transcription 1 (ABT1) Antibody (FITC) |
20-abx334567 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
Activator Of Basal Transcription 1 (ABT1) Antibody (Biotin) |
20-abx334568 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
Goat Activator of basal transcription 1(ABT1) ELISA kit |
E06A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Activator of basal transcription 1(ABT1) ELISA kit |
E06A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Activator of basal transcription 1(ABT1) ELISA kit |
E06A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Activator of basal transcription 1(ABT1) ELISA kit |
E02A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Activator of basal transcription 1(ABT1) ELISA kit |
E02A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Activator of basal transcription 1(ABT1) ELISA kit |
E02A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Activator of basal transcription 1(ABT1) ELISA kit |
E03A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Activator of basal transcription 1(ABT1) ELISA kit |
E03A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Activator of basal transcription 1(ABT1) ELISA kit |
E03A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Activator of basal transcription 1(ABT1) ELISA kit |
E04A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Activator of basal transcription 1(ABT1) ELISA kit |
E04A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Activator of basal transcription 1(ABT1) ELISA kit |
E04A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Activator of basal transcription 1(ABT1) ELISA kit |
E01A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Activator of basal transcription 1(ABT1) ELISA kit |
E01A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Activator of basal transcription 1(ABT1) ELISA kit |
E01A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Activator of basal transcription 1(ABT1) ELISA kit |
E08A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Activator of basal transcription 1(ABT1) ELISA kit |
E08A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Activator of basal transcription 1(ABT1) ELISA kit |
E08A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Activator of basal transcription 1(ABT1) ELISA kit |
E07A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Activator of basal transcription 1(ABT1) ELISA kit |
E07A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Activator of basal transcription 1(ABT1) ELISA kit |
E07A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Activator of basal transcription 1(ABT1) ELISA kit |
E09A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Activator of basal transcription 1(ABT1) ELISA kit |
E09A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Activator of basal transcription 1(ABT1) ELISA kit |
E09A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Bovine Activator of basal transcription 1, ABT1 ELISA KIT |
ELI-24538b |
Lifescience Market |
96 Tests |
EUR 928 |
Mouse Activator of basal transcription 1, Abt1 ELISA KIT |
ELI-24666m |
Lifescience Market |
96 Tests |
EUR 865 |
Human Activator of basal transcription 1, ABT1 ELISA KIT |
ELI-24776h |
Lifescience Market |
96 Tests |
EUR 824 |
Human Activator Of Basal Transcription 1 (ABT1) ELISA Kit |
abx385562-96tests |
Abbexa |
96 tests |
EUR 911 |
- Shipped within 5-12 working days.
|
BME 100X Amino Acids for Basal Medium Eagle (Modified). W/O L-glutamine. |
BML02-500ML |
Caisson Labs |
500 ml |
EUR 104 |
- Product line: Animal Cell Culture Media
- Product family: Basal Medium Eagle
|
Description: 100X Amino Acids for Basal Medium Eagle (Modified). Without L-glutamine. |
Guinea pig Activator of basal transcription 1(ABT1) ELISA kit |
E05A1165-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Activator of basal transcription 1(ABT1) ELISA kit |
E05A1165-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Activator of basal transcription 1(ABT1) ELISA kit |
E05A1165-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Anderson's Basal Salt |
CP001-010 |
GenDepot |
10x1L |
EUR 99 |
Anderson's Basal Salt |
CP001-500 |
GenDepot |
50L |
EUR 126 |
Anderson's Basal Salt |
CP002-010 |
GenDepot |
10X1L |
EUR 99 |
Anderson's Basal Salt |
CP002-500 |
GenDepot |
50L |
EUR 126 |
Pericyte Basal Media |
PGB002 |
Neuromics |
475 ml |
EUR 271 |
Astrocyte Basal Media |
PGB004 |
Neuromics |
500 ml |
EUR 271 |
ENDO Basal Media |
MED002 |
Neuromics |
500 ml |
EUR 207 |
500 ML GRACES'S INSECT BASAL MEDIUM (VAUGHN MOD.) WITH L-GLUTAMINE, WITHOUT INSECT HEMOLYMPH |
13-200-CV |
CORNING |
500 mL/pk |
EUR 315 |
Description: Specialty Media; Insect Media Products |
Advanced Medium |
C0003-04 |
Addexbio |
RT 500 mL Bottle |
EUR 103 |
Medium 199 |
C0012-01 |
Addexbio |
RT 500 mL Bottle |
EUR 105 |
Mounting Medium |
4300 |
Virostat |
3 ml |
EUR 180.5 |
Description: This is Mounting medium (non-fading) used for maintaining optimal conditions needed to obtain the maximum fluorescence emission from Fluorescein. |
Heller's Medium |
CP014-010 |
GenDepot |
10X1L |
EUR 99 |
Heller's Medium |
CP014-500 |
GenDepot |
50L |
EUR 126 |
Hoagland's Medium |
CP015-010 |
GenDepot |
10X1L |
EUR 99 |
Hoagland's Medium |
CP015-500 |
GenDepot |
50L |
EUR 126 |
NeuroProgenitor Medium |
NM42400 |
Neuromics |
125 ml |
EUR 304 |
M9 Medium |
SD7024 |
Bio Basic |
250g |
EUR 71.75 |
- Product category: Culture Media/Medium
|
M9CA Medium |
SD7025 |
Bio Basic |
250g |
EUR 71.75 |
- Product category: Culture Media/Medium
|
YM Medium |
SD7031 |
Bio Basic |
250g |
EUR 70.45 |
- Product category: Culture Media/Medium
|
TYGPN Medium |
SD7032 |
Bio Basic |
250g |
EUR 70.01 |
- Product category: Culture Media/Medium
|
M63 Medium |
SD7033 |
Bio Basic |
250g |
EUR 71.75 |
- Product category: Culture Media/Medium
|
A Medium |
DJ1018 |
Bio Basic |
100g |
EUR 84.8 |
- Product category: Culture Media/Medium
|
Basal Body Marker antibody |
10-2480 |
Fitzgerald |
250 ug |
EUR 492 |
Description: Mouse monoclonal Basal Body Marker antibody |
Basal Cell Cytokeratin antibody |
10R-7959 |
Fitzgerald |
100 ug |
EUR 370 |
Description: Mouse monoclonal Basal Cell Cytokeratin antibody |
ExpressMax™ Basal Salts |
145 |
AthenaES |
500 g |
EUR 86 |
DKW Basal Salt Mixture |
CP007-010 |
GenDepot |
10X1L |
EUR 99 |
DKW Basal Salt Mixture |
CP007-500 |
GenDepot |
50L |
EUR 126 |
Cancer of the breast, basal-like breast carcinoma, 48 cases (1.5mm), set 1 |
BRC965 |
Pantomics |
1 |
EUR 410 |
Description: Breast cancer tissue array, basal-like breast carcinoma, 48 cases (1.5mm), set 1, 96 cores, 48 cases, containing 35 cases basal-like, 3 cases luminal A, 3 cases luminal B, 4 cases Her2 overexpression types and 1 case Adenoid cystic carcinoma for positive control, with grading, TNM staging, and ER, PR, HER2, P53, EGFR, Ki67,CK5/6 and Nestin IHC data. |
Insect Cell Medium: TNM-FH Insect Culture Medium |
ABP-MED-10001 |
Allele Biotech |
1 liter |
Ask for price |
- Product line: Cell Culture Reagents
- Brand:
|
Insect Cell Medium: Serum-Free Insect Culture Medium |
ABP-MED-10002 |
Allele Biotech |
1 liter |
Ask for price |
- Product line: Cell Culture Reagents
- Brand:
|
Insect Cell Medium: Grace?s Insect Medium (Unsupplemented) |
ABP-MED-10004 |
Allele Biotech |
1 liter |
Ask for price |
- Product line: Cell Culture Reagents
- Brand:
|
Aqueous Mounting Medium |
AR1018 |
BosterBio |
10mL X5 (Enough for 800-1200 assays) |
EUR 80 |
Antifade Mounting Medium |
AR1109 |
BosterBio |
10mL (for 1000 assays) |
EUR 65 |
AddexBio Cryopreservation Medium |
C0002-20mL |
Addexbio |
RT vial |
EUR 104 |
Hepatocyte Maintenance Medium |
HM42600 |
Neuromics |
100 ml |
EUR 409 |
Neuron Growth Medium |
HNM001 |
Neuromics |
500 ml |
EUR 331 |
RPMI 1640 Medium |
abx098879-500ml |
Abbexa |
500 ml |
EUR 175 |
- Shipped within 5-10 working days.
|
SuperMOUNT? Mounting Medium |
1211-20 |
Biovision |
|
EUR 201 |
EverBrite Mounting Medium |
23001 |
Biotium |
10mL |
EUR 178 |
Description: Minimum order quantity: 1 unit of 10mL |
MCDB 131 Medium |
CM034-050 |
GenDepot |
500ml |
EUR 85 |
MCDB 131 Medium |
CM034-300 |
GenDepot |
6x500ml |
EUR 165 |
MCDB 131 Medium |
CM034-310 |
GenDepot |
10x500ml |
EUR 219 |
MCDB 131 Medium |
CM034-320 |
GenDepot |
20x500ml |
EUR 340 |
MCDB 131 Medium |
CM034-350 |
GenDepot |
50x500ml |
EUR 585 |
Williams' Medium
E |
CM063-050 |
GenDepot |
500ml |
EUR 91 |
Williams' Medium
E |
CM063-300 |
GenDepot |
6x500ml |
EUR 266 |
Williams' Medium
E |
CM063-310 |
GenDepot |
10x500ml |
EUR 313 |
Williams' Medium
E |
CM063-320 |
GenDepot |
20x500ml |
EUR 604 |
Williams' Medium
E |
CM063-350 |
GenDepot |
50x500ml |
EUR 975 |
Cereal Crops Medium |
CP003-005 |
GenDepot |
5L |
EUR 113 |
Cereal Crops Medium |
CP003-010 |
GenDepot |
10X1L |
EUR 169 |
Kao Michayluk Medium |
CP017-010 |
GenDepot |
10X1L |
EUR 99 |
Kao Michayluk Medium |
CP017-500 |
GenDepot |
50L |
EUR 126 |
Orchid Maintenance Medium |
CP037-010 |
GenDepot |
10X1L |
EUR 109 |
Orchid Maintenance Medium |
CP037-500 |
GenDepot |
50L |
EUR 138 |
Woody Plants Medium |
CP040-010 |
GenDepot |
10X1L |
EUR 101 |
Woody Plants Medium |
CP040-500 |
GenDepot |
50L |
EUR 126 |
Sepadextran-25 Medium |
SD25M-100 |
ABTBeads |
100 g |
EUR 271 |
Sepadextran-25 Medium |
SD25M-500 |
ABTBeads |
500 g |
EUR 1036 |
Sepadextran-50 Medium |
SD50M-100 |
ABTBeads |
100 g |
EUR 344 |
Sepadextran-50 Medium |
SD50M-500 |
ABTBeads |
500 g |
EUR 1285 |
Schwann Growth Medium |
SGM001 |
Neuromics |
500 ml |
EUR 244 |
H Medium Broth |
DJ1019 |
Bio Basic |
100g |
EUR 60.88 |
- Product category: Culture Media/Broth
|
Basal Cell Adhesion Molecule/CD239 |
PR27244 |
Neuromics |
2 ug |
EUR 191 |
Human Cartilage Growth Medium PrimaCell: Normal Articular Cartilage Growth Medium |
9-46043 |
CHI Scientific |
5 x 100 ml |
Ask for price |
Rat Cartilage Growth Medium PrimaCell: Normal Articular Cartilage Growth Medium |
9-25023 |
CHI Scientific |
5 x 100 ml |
Ask for price |
Basal Cell Adhesion Molecule (BCAM) Antibody |
20-abx129079 |
Abbexa |
-
EUR 411.00
-
EUR 133.00
-
EUR 1149.00
-
EUR 565.00
-
EUR 314.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
- Shipped within 5-7 working days.
|
Basal Cell Adhesion Molecule (BCAM) Antibody |
20-abx327530 |
Abbexa |
|
|
- Shipped within 5-10 working days.
|
Basal Cell Adhesion Molecule (BCAM) Antibody |
20-abx339595 |
Abbexa |
|
|
- Shipped within 5-10 working days.
|
Basal Cell Adhesion Molecule (BCAM) Antibody |
20-abx333957 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
Basal Cell Adhesion Molecule (BCAM) Antibody |
20-abx213158 |
Abbexa |
|
|
- Shipped within 5-10 working days.
|
Basal Cell Adhesion Molecule (BCAM) Antibody |
20-abx171384 |
Abbexa |
|
|
|
Recombinant Basal Cell Adhesion Molecule (BCAM) |
4-RPB716Hu01 |
Cloud-Clone |
-
EUR 476.32
-
EUR 230.00
-
EUR 1511.20
-
EUR 570.40
-
EUR 1040.80
-
EUR 382.00
-
EUR 3628.00
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
- Uniprot ID: P50895
- Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
- Form: Freeze-dried powder
- Predicted Molecular Mass (KD): 28.7kDa
- Isoelectric Point: Inquire
|
Description: Recombinant Human Basal Cell Adhesion Molecule expressed in: E.coli |
Alpha-glia Expansion Medium |
AGEM-001 |
Neuromics |
500 ml |
EUR 375 |
Formulated RPMI-1640 Medium |
C0004-01 |
Addexbio |
RT 500 mL Bottle |
EUR 98 |
Optimized RPMI-1640 Medium |
C0004-02 |
Addexbio |
RT 500 mL Bottle |
EUR 100 |
Leibovitz's L-15 Medium |
C0006-01 |
Addexbio |
RT 500 mL Bottle |
EUR 108 |
Stellate Cell Medium/kit |
C0009-01 |
Addexbio |
RT 500 mL Bottle |
EUR 227 |
Cervical Epithalial cell medium |
C0011-01 |
Addexbio |
RT 500 mL Bottle |
EUR 239 |
Medium 199/BCDB 105 |
C0012-02 |
Addexbio |
RT 500 mL Bottle |
EUR 151 |
Human Epithelial Cell Medium |
ECM001 |
Neuromics |
500 mL |
EUR 323 |
The current work strongly means that the mitochondrion is a vital goal for OA chondrocyte injury induced by TNF-α and the PQQ safety from this injury ameliorates mitochondrial dysfunction induced by TNF-α. PQQ may be a possible chemical for OA intervention.
Leave a Comment