Interleukin-1 receptor-associated kinase-3 (IRAK3) has a particular position in regulating irritation. Nevertheless, the practical position of IRAK3 and regulatory mechanism underlying the pathogenesis of osteoarthritis (OA) stay unclear. Right here, we first discovered that IRAK3 was upregulated, whereas miR-33b-3p was downregulated within the cartilage of OA sufferers and IL-1β-induced CHON-001 cells.
IRAK3 was confirmed because the direct goal of miR-33b-3p and negatively regulated by miR-33b-3p. There was an inverse correlation between IRAK3 mRNA expression and miR-33b-3p expression in OA cartilage tissues. The in vitro practical experiments confirmed that miR-33b-3p overexpression precipitated a exceptional enhance in viability, a big lower in inflammatory mediators (IL-1β and TNF-α), and apoptosis in IL-1β-induced CHON-001 cells. Importantly, IRAK3 knockdown imitated, whereas overexpression reversed the results of miR-33b-3p on IL-1β-induced irritation and apoptosis in CHON-001 cells. Collectively, miR-33b-3p considerably alleviated IL-1β-induced irritation and apoptosis by downregulating IRAK3, which can function a promising goal for OA.
USP7 Inhibition Alleviates H 2 O 2-Induced Damage in Chondrocytes through Inhibiting NOX4/NLRP3 Pathway
Osteoarthritis (OA), the most typical type of arthritis, is a quite common joint illness that usually impacts middle-aged to aged folks. Nevertheless, present remedy choices for OA are predominantly palliative. Thus, understanding its pathological course of and exploring its potential therapeutic approaches are of nice significance. Rat chondrocytes have been remoted and uncovered to hydrogen peroxide (H2O2) to imitate OA. The consequences of H2O2 on ubiquitin-specific protease 7 (USP7) expression, reactive oxygen species (ROS) ranges, proliferation, inflammatory cytokine launch, and pyroptosis have been measured.
USP7 was knocked down (KD) or overexpressed to research the position of USP7 in OA. Co-immunoprecipitation (Co-IP) was used to check the interplay between USP7 and NAD(P)H oxidases (NOX)four in addition to NOX4 ubiquitination. NOX4 inhibitor was utilized to check the involvement of NOX4 in USP7-mediated OA improvement. USP7 inhibitor was given to OA animals to additional examine the position of USP7 in OA in vivo.
Furthermore, H2O2 remedy considerably elevated USP7 expression, enhanced ROS ranges, and inhibited proliferation in rat chondrocytes. The overexpression of USP7 enhanced pyroptosis, ROS manufacturing, interleukin (IL)-1β and IL-18 ranges, and the expression degree of NLRP3, GSDMD-N, energetic caspase-1, pro-caspase-1, matrix metalloproteinases (MMP) 1, and MMP13, which was abolished by ROS inhibition. The USP7 KD protected rat chondrocytes in opposition to H2O2-induced harm. Co-IP outcomes confirmed that USP7 interacted with NOX4, and USP7 KD enhanced NOX4 ubiquitinylation.
The inhibition of NOX4 blocked the pro-OA impact of USP7. Furthermore, the USP7 inhibitor given to OA animals suppressed OA in vivo. USP7 inhibited NOX4 ubiquitination for degradation which results in elevated ROS manufacturing. ROS subsequently prompts NLPR3 inflammasome, resulting in enhanced manufacturing of IL-1β and IL-18, GSDMD-N-dependent pyroptosis, and extracellular matrix reworking. Thus, UPS7 contributes to the development of OA through NOX4/ROS/NLPR3 axis.
Acid-Sensing Ion Channel-1a in Articular Chondrocytes and Synovial Fibroblasts: A Novel Therapeutic Goal for Rheumatoid Arthritis
Acid-sensing ion channel 1a (ASIC1a) is a member of the extracellular H+-activated cation channel household. Rising proof has urged that ASIC1a performs a vital position within the pathogenesis of rheumatoid arthritis (RA). Particularly, ASIC1a might promote irritation, synovial hyperplasia, articular cartilage, and bone destruction; these result in the development of RA, a continual autoimmune illness characterised by continual synovial irritation and extra-articular lesions.
On this evaluation, we offered a quick overview of the molecular properties of ASIC1a, together with the essential organic traits, tissue and cell distribution, channel blocker, and elements influencing the expression and performance, and centered on the potential therapeutic targets of ASIC1a in RA and doable mechanisms of blocking ASIC1a to enhance RA signs, akin to regulation of apoptosis, autophagy, pyroptosis, and necroptosis of articular cartilage, and synovial irritation and invasion of fibroblast-like cells in synovial tissue.

Protecting Impact of Pyrroloquinoline Quinone on TNF-α-induced Mitochondrial Damage in Chondrocytes
Osteoarthritis (OA) is a degenerative illness characterised by matrix degradation and cell loss of life resulting in a gradual lack of articular cartilage integrity. As a bacterial synthesis of quinine, pyrroloquinoline quinone (PQQ) is a robust redox cofactor with a wide range of organic advantages, together with antioxidant, anti-inflammation-induced mitochondrial metabolism regulation.
This examine was designed to research the impact of PQQ on TNF-α-induced mitochondrial injury in chondrocytes. Chondrocytes remoted from C57BL/6 mice have been uncovered to TNF-α 50 ng/mL, TNF-α 50 ng/mL + PQQ 10 µmol/L for 24 h. Then, morphological examine, practical examine and mechanism examine have been taken. The outcomes revealed TNF-α-induced chondrocyte mitochondrion injury could possibly be lowered by utility of PQQ, evidenced by elevated variety of mitochondria, well-kept mtDNA integrity, preserved ATP degree, reestablished mitochondrial membrane potential, and prevented mitochondrial perform.
ENDO Basal Media |
MED002 |
Neuromics |
500 ml |
EUR 248.4 |
Pericyte Basal Media |
PGB002 |
Neuromics |
475 ml |
EUR 325.2 |
Astrocyte Basal Media |
PGB004 |
Neuromics |
500 ml |
EUR 325.2 |
Medium 199 |
C0012-01 |
Addexbio |
RT 500 mL Bottle |
EUR 126 |
FRIIS BASE Medium, Liquid |
F2485-100 |
GenDepot |
100ml |
Ask for price |
FRIIS BASE Medium, Liquid |
F2485-500 |
GenDepot |
500ml |
Ask for price |
Heller's Medium |
CP014-010 |
GenDepot |
10X1L |
EUR 118.8 |
Heller's Medium |
CP014-500 |
GenDepot |
50L |
EUR 151.2 |
anti-Activator of basal transcription 1 |
YF-PA18596 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
anti-Activator of basal transcription 1 |
YF-PA18597 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
anti-Activator of basal transcription 1 |
YF-PA18598 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
anti-Activator of basal transcription 1 |
YF-PA18599 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to Activator of basal transcription 1 |
Insect Cell Medium: TNM-FH Insect Culture Medium |
ABP-MED-10001 |
Allele Biotech |
1 liter |
Ask for price |
|
Mounting Medium |
4300 |
Virostat |
3 ml |
EUR 216.6 |
Description: This is Mounting medium (non-fading) used for maintaining optimal conditions needed to obtain the maximum fluorescence emission from Fluorescein. |
Advanced Medium |
C0003-04 |
Addexbio |
RT 500 mL Bottle |
EUR 123.6 |
Hoagland's Medium |
CP015-010 |
GenDepot |
10X1L |
EUR 118.8 |
Hoagland's Medium |
CP015-500 |
GenDepot |
50L |
EUR 151.2 |
Insect Cell Medium: Serum-Free Insect Culture Medium |
ABP-MED-10002 |
Allele Biotech |
1 liter |
Ask for price |
|
RPMI 1640 Medium |
abx098879-500ml |
Abbexa |
500 ml |
EUR 210 |
|
MCDB 131 Medium |
CM034-050 |
GenDepot |
500ml |
EUR 102 |
MCDB 131 Medium |
CM034-300 |
GenDepot |
6x500ml |
EUR 198 |
MCDB 131 Medium |
CM034-310 |
GenDepot |
10x500ml |
EUR 262.8 |
MCDB 131 Medium |
CM034-320 |
GenDepot |
20x500ml |
EUR 408 |
MCDB 131 Medium |
CM034-350 |
GenDepot |
50x500ml |
EUR 702 |
Medium 199/BCDB 105 |
C0012-02 |
Addexbio |
RT 500 mL Bottle |
EUR 181.2 |
Insect Cell Medium: Grace?s Insect Medium (Unsupplemented) |
ABP-MED-10004 |
Allele Biotech |
1 liter |
Ask for price |
|
BPS Medium 1 |
79259 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid BPS Medium is optimized for use with many BPS Reporter Kits including_x000D_ • 60612: AP1 Reporter Kit (JNK Pathway)_x000D_ • 60514: ARE Reporter Kit (Nrf2 Antioxidant Pathway)_x000D_ • 60611: CRE/CREB Reporter Kit (cAMP/PKA Signaling Pathway)_x000D_ • 60614: NF-κB Reporter Kit (NF-κB Signaling Pathway)_x000D_ • 60509: Notch1/CSL Reporter Kit (Notch Signaling Pathway)_x000D_ • 60654: SBE Reporter Kit (TGFβ/SMAD signaling pathway)_x000D_ • 60511: SRE Reporter Kit (MAPK/ERK Signaling Pathway)_x000D_ • 60500: TCF/LEF Reporter Kit (Wnt Signaling Pathway) |
BPS Medium 7 |
79260 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid BPS Medium is optimized for use with select BPS reporter kits. |
BPS Medium 8 |
79385 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid BPS Medium is optimized for use with the CSF1R/SRE Reporter Kit (BPS Bioscience, #79379). |
Thaw Medium 8 |
79652-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines including NF- κB Reporter (Luc) – THP-1 Cell Line, #79645 |
Thaw Medium 8 |
79652-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines including NF- κB Reporter (Luc) – THP-1 Cell Line, #79645 |
Thaw Medium 9 |
79665-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including_x000D_• CRE/CREB Reporter Lentivirus #79580 _x000D_• NF-κB Reporter Luciferase Reporter Lentivirus #79564 |
Thaw Medium 9 |
79665-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, using • CRE/CREB Reporter Lentivirus #79580 _x000D_• NF-κB Reporter Luciferase Reporter Lentivirus #79564 |
Thaw Medium 10 |
79704-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines. |
Thaw Medium 10 |
79704-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines. |
Thaw Medium 11 |
79976-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines._x000D_Optimized for Use With:_x000D_NF- κB Reporter (Luc) - Raw 264.7 Cell line (BPS Bioscience 79978) |
Thaw Medium 11 |
79976-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines._x000D_Optimized for Use With:_x000D_NF- κB Reporter (Luc) - Raw 264.7 Cell line (BPS Bioscience 79978) |
Thaw Medium 12 |
78074-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including: • Cas9-expressing MDA-MB-231 cells (BPS Bioscience #78069) |
Thaw Medium 12 |
78074-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including: • Cas9-expressing MDA-MB-231 cells (BPS Bioscience #78069) |
Thaw Medium 14 |
78397-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines. |
Thaw Medium 14 |
78397-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines. |
Thaw Medium 15 |
78412-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines. |
Thaw Medium 15 |
78412-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines. |
Thaw Medium 16 |
78647-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for use with tetracycline-inducible system. |
Thaw Medium 16 |
78647-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for use with tetracycline-inducible system. |
Thaw Medium 4 |
60181-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• CFTR - HEK 293 Recombinant Cell Line #60506• Nav1.8/β2 - HEK293 Recombinant Cell Line #60521• NaV1.7-HEK293 Recombinant Cell Line #60607 |
Thaw Medium 4 |
60181-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• CFTR - HEK 293 Recombinant Cell Line #60506• Nav1.8/β2 - HEK293 Recombinant Cell Line #60521• NaV1.7-HEK293 Recombinant Cell Line #60607 |
Thaw Medium 5 |
60182-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Gli Reporter - NIH3T3 Recombinant Cell line (Hedgehog Pathway) #60409 |
Thaw Medium 5 |
60182-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Gli Reporter - NIH3T3 Recombinant Cell line (Hedgehog Pathway) #60409 |
Thaw Medium 6 |
60183-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520• NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 • RARα Reporter - HEK293 Recombinant Cell Line #60503 • RARβ Reporter - HEK293 Recombinant Cell Line #60603 • RARγ Reporter - HEK293 Reporter Cell Line #60604 |
Thaw Medium 6 |
60183-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520• NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 • RARα Reporter - HEK293 Recombinant Cell Line #60503 • RARβ Reporter - HEK293 Recombinant Cell Line #60603 • RARγ Reporter - HEK293 Reporter Cell Line #60604 |
Thaw Medium 2 |
60184-1 |
BPS Bioscience |
100 ml |
EUR 150 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating BPS Bioscience's Jurkat-based cell lines, including• PD-1/NFAT Reporter-Jurkat cell #60535• NFAT Reporter (Luc) - Jurkat Cell Line #60621• NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line #60651• ADCC Bioassay Effector Cell F variant (Low Affinity) #60540• ADCC Bioassay Effector Cell V variant (High Affinity) #60541Note: once cells are well-established, switch to the appropriate cell growth medium. |
Thaw Medium 2 |
60184-2 |
BPS Bioscience |
500 ml |
EUR 675 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including_x000D__x000D_• PD-1/NFAT Reporter-Jurkat cell #60535_x000D__x000D_• NFAT Reporter (Luc) - Jurkat Cell Line #60621_x000D__x000D_• NF-ĸB-Luciferase Reporter (Luc) - Jurkat Cell Line #60651_x000D__x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) #60540_x000D__x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) #60541_x000D__x000D_Note: once cells are well-established, switch to the appropriate cell growth medium. |
Thaw Medium 7 |
60185-1 |
BPS Bioscience |
100 ml |
EUR 140 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520 • NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 |
Thaw Medium 7 |
60185-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including • Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520 • NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 |
Thaw Medium 3 |
60186-1 |
BPS Bioscience |
100 ml |
EUR 150 |
Description: This liquid Cell Thaw Medium is optimized for thawing and plating BPS Bioscience's CHO cell-based recombinant cell lines, including• TCR Activator - CHO Recombinant Cell line #60539 • TCR activator / PD-L1 - CHO Recombinant Cell line #60536 It is designed for use in a 37°C incubator with an atmosphere of 5% CO2/95% air. Note: once cells are well established, switch to an appropriate cell growth medium. |
Thaw Medium 3 |
60186-2 |
BPS Bioscience |
500 ml |
EUR 645 |
Description: This liquid thaw medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including_x000D__x000D_• TCR Activator - CHO Recombinant Cell line #60539 _x000D_• TCR activator / PD-L1 - CHO Recombinant Cell line #60536 _x000D__x000D_• CD27 CHO-K1 Stable Recombiant Cell Line #60624 _x000D__x000D_• PD-L1 - CHO Recombinant Cell Line #60543 _x000D__x000D_• NF-κB Reporter (Luc) - CHO-K1 Recombinant Cell Line #60622_x000D_• CD137L (4-1BBL) CHO-K1 Recombinant Cell Line #60523_x000D__x000D_It is designed for use in a 37°C incubator with an atmosphere of 5% CO2/95% air. _x000D_Note: once cells are well established, switch to an appropriate cell growth medium._x000D_ |
Thaw Medium 1 |
60187-1 |
BPS Bioscience |
100 ml |
EUR 155 |
Description: This liquid HEK293 Cell Thawing Medium is optimized for thawing and plating BPS Bioscience's HEK293 recombinant cell lines. |
Thaw Medium 1 |
60187-2 |
BPS Bioscience |
500 ml |
EUR 695 |
Description: This liquid Thaw Medium is optimized for thawing and plating BPS Bioscience's HEK293 recombinant cell lines. |
Assay Medium 1B |
79617-1 |
BPS Bioscience |
100 ml |
EUR 135 |
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TGF/SMAD Signaling Pathway SBE Reporter - HEK293 Cell Line #60653 _x000D_• AP-1 Reporter - HEK293 Recombinant Cell Line (JNK signaling pathway) #60405 |
Assay Medium 1B |
79617-2 |
BPS Bioscience |
500 ml |
EUR 675 |
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TGF/SMAD Signaling Pathway SBE Reporter - HEK293 Cell Line #60653 _x000D_• AP-1 Reporter - HEK293 Recombinant Cell Line (JNK signaling pathway) #60405 |
Assay Medium 2B |
79619-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line -#60628 |
Assay Medium 2B |
79619-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line -#60628 |
Assay Medium 5A |
79620-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience cell lines. |
Assay Medium 5A |
79620-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience cell lines. |
Assay Medium 2A |
79621-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) - Jurkat Recombinant Cell Line #60540 _x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) - Jurkat Recombinant Cell Line #60541 |
Assay Medium 2A |
79621-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) - Jurkat Recombinant Cell Line #60540 _x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) - Jurkat Recombinant Cell Line #60541 |
Assay Medium 2C |
79623-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TIGIT / NFAT Reporter - Jurkat Recombinant Cell Line - #60538_x000D_• CD155/TCR Activator - CHO Recombinant Cell Line -#60548 |
Assay Medium 2C |
79623-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TIGIT / NFAT Reporter - Jurkat Recombinant Cell Line, #60538 • CD155/TCR Activator - CHO Recombinant Cell Line, #60548 |
Assay Medium 7B |
79718-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience cell lines._x000D_Optimized for use with Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway), #60520 |
Assay Medium 7B |
79718-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience cell lines._x000D_Optimized for use with Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway), #60520 |
Assay Medium 1A |
79805-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including TrkA / SRE Reporter - HEK293 Recombinant Cell Line (#79798) |
Assay Medium 1A |
79805-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including TrkA / SRE Reporter - HEK293 Recombinant Cell Line (#79798) |
Assay Medium 2C |
78544-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Assay Medium 2C |
78544-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Assay Medium 7A |
78673-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay |
Assay Medium 7A |
78673-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay |
Assay Medium 1C |
78674-1 |
BPS Bioscience |
100 ml |
EUR 120 |
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay. |
Assay Medium 1C |
78674-2 |
BPS Bioscience |
500 ml |
EUR 600 |
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay. |
H Medium Broth |
DJ1019 |
Bio Basic |
100g |
EUR 73.06 |
|
NeuroProgenitor Medium |
NM42400 |
Neuromics |
125 ml |
EUR 364.8 |
Growth Medium 1A |
79528 |
BPS Bioscience |
500 ml |
EUR 715 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 3B |
79529 |
BPS Bioscience |
500 ml |
EUR 715 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 2B |
79530 |
BPS Bioscience |
500 ml |
EUR 700 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for use with:_x000D_IL-2 Jurkat Luciferase Reporter - Jurkat Cell Line #60481 NF-kB Luciferase Reporter - Jurkat Cell Line #60651 Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line #60628 |
Growth Medium 1B |
79531 |
BPS Bioscience |
500 ml |
EUR 755 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 1C |
79532 |
BPS Bioscience |
500 ml |
EUR 755 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 1K |
79533 |
BPS Bioscience |
500 ml |
EUR 715 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 5A |
79534 |
BPS Bioscience |
500 ml |
EUR 715 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 4A |
79535 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 1D |
79536 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 3C |
79537 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 1E |
79538 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 3D |
79539 |
BPS Bioscience |
500 ml |
EUR 735 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 1F |
79540 |
BPS Bioscience |
500 ml |
EUR 755 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 5B |
79541 |
BPS Bioscience |
500 ml |
EUR 685 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 6A |
79542 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 7A |
79543 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 1G |
79544 |
BPS Bioscience |
500 ml |
EUR 755 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Optimized for use with GR-GAL4 Reporter (Luc) -HEK293 Recombinant Cell Line (Glucocorticoid Receptor Pathway), #60655, and CD137/NF-κB Reporter - HEK293 Recombinant Cell Line, #79289 |
Growth Medium 7B |
79545 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_Optimized for use with Myc Reporter (Luc) - HCT116 Recombinant Cell Line, #60520. |
Growth Medium 1H |
79546 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: T-Rex HEK293 Recombinant Cell Line (BPS Bioscience, #71227) |
Growth Medium 1J |
79552 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 3E |
79553 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 4B |
79554 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including: • Nav1.8/β2 - HEK293 Recombinant Cell Line #60521 |
Growth Medium 1L |
79555 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 2C |
79592 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for use with:_x000D_ GITR/NF-κB Luciferase Reporter (Luc) - Jurkat Cell Line #60546_x000D_ |
Growth Medium 4C |
79631 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including: • CFTR - HEK 293 Recombinant Cell Line - #60506 |
Growth Medium 2E |
79638 |
BPS Bioscience |
500 ml |
EUR 715 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for use with:_x000D_CRE/CREB Reporter (Luc) - Jurkat Cell Line - #79636_x000D_ |
Growth Medium 2D |
79639 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: TCR Activator - Raji Cell Line (BPS Bioscience, #60556) |
Growth Medium 8A |
79653 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for Use With: _x000D_NF- κB Reporter (Luc) - THP-1 Cell Line - #79645 |
Growth Medium 6B |
79657 |
BPS Bioscience |
500 ml |
EUR 700 |
Description: This liquid Growth Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including: • NF-kB Reporter (Luc) - A549 Stable Cell Line #60625 |
Growth Medium 2F |
79669 |
BPS Bioscience |
500 ml |
EUR 685 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_ Optimized for use with ICOS NFAT - Jurkat Cell Line, #79668 |
Growth Medium 1M |
79723 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_ Optimized for Use With: CSF1R / SRE - Reporter HEK293 Recombinant Cell Line (#79380) |
Growth Medium 2G |
79734 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_Optimized for use with: ADCC Bioassay Effector Cell - Mouse - Jurkat Recombinant Cell Line, (BPS #79733) |
Growth Medium 2H |
79784 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_ Optimized for use with: Anti-BCMA CAR Jurkat/NFAT (Luciferase) Reporter Cell Line (BPS #79694) |
Growth Medium 1N |
79801 |
BPS Bioscience |
500 ml |
EUR 755 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol. |
Growth Medium 2J |
79812 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_ Optimized for use with: LAG3 / IL-2 Reporter - Jurkat Recombinant Cell Line (BPS# 79813) |
Growth Medium 3F |
79829 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_Optimized for Use With: BCMA / GLuc - CHO Recombinant Cell Line #79830 |
Growth Medium 3G |
79882 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines and lentivirus._x000D_Optimized for Use with_x000D_ FcGRIIIA (CD16a) Lentivirus, FcER1G Lentivirus |
Growth Medium 3J |
79974 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_Optimized for use with: ACE2 - CHO Recombinant Cell Line (BPS Bioscience #79959) |
Growth Medium 3K |
78041 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. _x000D_Optimized for Use With_x000D_ CD19 / BCMA / Firefly Luciferase - CHO Recombinant Cell Line (BPS Bioscience, #78030) |
Growth Medium 7C |
78076 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools_x000D_Optimized for use With: Cas9-expressing HCT116 cell pool (BPS Bioscience, #78073) |
Growth Medium 6C |
78077 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools._x000D_Optimized for use with: Cas9-expressing A549 cell pool (BPS Bioscience, #78072) |
Growth Medium 2K |
78078 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools._x000D_Optimized for use with: Cas9-expressing Jurkat cell pool (BPS Bioscience, #78070) Cas9-expressing Raji cell pool (BPS Bioscience, #78071) |
Growth Medium 2L |
78094 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools._x000D_Optimized for Use With: CRISPRa (SAM) Jurkat Cell Pool (BPS Bioscience, #78080) |
Growth Medium 1P |
78095 |
BPS Bioscience |
500 ml |
EUR 685 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_Optimized for Use With:_x000D_ TMPRSS2 - Vero E6 Recombinant Cell Line (BPS Bioscience, #78081) |
Growth Medium 1Q |
78096 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools_x000D_Optimized for Use With:_x000D_ Cas9-Expressing Neuro2A Cell Pool (BPS Bioscience, #78087) |
Growth Medium 3L |
78104 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 1R |
78180 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools.Optimized for Use With: Cas9-Expressing MCF7 Cell Pool (BPS Bioscience #78179) |
Growth Medium 2M |
78181 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 2N |
78196 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 7D |
78200 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines |
Growth Medium 1S |
78221 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: CRISPRa (SAM) HeLa Cell Line (BPS Bioscience, #78193), CRISPRa (SAM) HepG2 Cell Line (BPS Bioscience, #78194) |
Growth Medium 6D |
78222 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: CRISPRa (SAM) HEK293 Cell Line (BPS Bioscience, #78192) |
Growth Medium 2P |
78354 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 3M |
78377 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 1T |
78379 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 2Q |
78380 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 6E |
78385 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 2R |
78411 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 2S |
78430 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 3N |
78534 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 6F |
78540 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 1U |
78548 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines |
Growth Medium 1V |
78551 |
BPS Bioscience |
500 ml |
EUR 650 |
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
Growth Medium 3A |
60188 |
BPS Bioscience |
500 ml |
EUR 755 |
Description: This liquid Growth Medium is a complete medium optimized to culture select CHO and CHO-K1 cell lines. |
Growth Medium 2A |
60190 |
BPS Bioscience |
500 ml |
EUR 755 |
Description: This liquid Growth Medium is a complete medium optimized to culture select Jurkat cell lines. |
The current work strongly means that the mitochondrion is a vital goal for OA chondrocyte injury induced by TNF-α and the PQQ safety from this injury ameliorates mitochondrial dysfunction induced by TNF-α. PQQ may be a possible chemical for OA intervention.
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